Abstract: In order to evaluate the feasibility of addition of urease inhibitor (hydroquinone,HQ) and nitrification inhibitors(DCD) into urea solution applied in drip fertigation,a pot experiment with maize as a test crop was conducted under greenhouse condition.HQ and DCD were supplied through drip fertigation and soil application before sowing,and the dosages were 0.3%,0.5% and 1.0% of urea application rate for HQ and 2.5%,5.0% and 10.0% of urea rate for DCD.The results indicated that,under drip fertigation with urea solution,0.3%HQ,0.5%HQ and 5.0%DCD could significantly increase N use efficiency(NUE) as compared to fertigation with urea alone,and the NUE were 74.8%,75.8%,75.3% respectively;When HQ and DCD were applied to soil under drip irrigation,HQ showed no positive effect on NUE.However,DCD increased significantly the NUE of urea with data as 61.9%,54.6% and 58.4%,respectively.The NUE of urea with HQ and DCD application in drip fertigation system were higher than that with HQ and DCD applied into soil before sowing under drip irrigation.