Abstract: The effect functions of NPK application on economical yield, fertilization benefit and N ratio of split application at different growing periods of headed cabbage(Brassica oleracea var. capitata) were studied by the field experiments with 311-A best regression design of supposed saturation and 3, 2 saturated design of single shape check. The results showed that the best NPK application of headed cabbage with maximum economical yield of 73.877 t/hm2 was N 277.83, P2O5 64.59 and K2O 126.53 kg/hm2, the best NPK application with the best fertilization benefit of 46085.87 yuan/hm2 and higher economical yield of 73.786 t/hm2 was N 267.15, P2O5 62.63 and K2O 121.56 kg/hm2, and better ratio of N split application as basal dressing, and former and latter topdressing for higher expecting economical yield of 74.946 t/hm2 was 0.3840∶ 0.3554∶ 0.2606, and the N rates were 106.75, 98.80 and 72.45 kg/hm2, respectively.