Abstract: The 3414 fertilizer experiment for high fertilizer efficiency was designed to investigate N, P and K fertilizer effects on millet yield, and to simulate the optimum fertilizer recommendation rates by the established models for scientific fertilization. The results show that the application of fertilizer significantly increases the yield of millet, with a highest yieldincrement rate of 52.31% and with a lowest one in the case of no and excessive N which indicates a suitable application rate of N fertilizer is an important factor to influencemillet yield. The combined applications of N, P and K have interactions with each other and promote millet yield with the order of N＞PK respectively. Any excessive applicationof the three factors could result in reducing the yield significantly. Through establishing the fertilizer efficiency models based on the yield, the recommended optimumfertilizer amounts of N, P2O5 and K2O are 121.61, 78.09, 24.23 kg/ha respectively. The suitable ratio of N∶P2O5∶K2O is 1∶0.64∶0.20.